CLINICAL SIGNIFICANCE OF NON-INVASIVE DIAGNOSTIC METHODS IN THE MONITORING OF DRUG-INDUCED LIVER INJURY

Malika Khusanovna Tolibjonova; Oripov Nuriddin Najmiddinovich

CLINICAL SIGNIFICANCE OF NON-INVASIVE DIAGNOSTIC METHODS IN THE MONITORING OF DRUG-INDUCED LIVER INJURY

Authors

Malika Khusanovna Tolibjonova DSc, Associate Professor, Department of Propedeutics of Internal Diseases No.1, Tashkent State Medical University, Tashkent, Uzbekistan
Oripov Nuriddin Najmiddinovich PhD, Assistant, Department of Propedeutics of Internal Diseases No.1, Tashkent State Medical University, Tashkent, Uzbekistan

Keywords:

drug-induced liver injury, DILI, non-invasive diagnostics, elastometry, biomarkers, humoral factors, hepatotoxicity, liver fibrosis, propaedeutics of internal diseases.

Abstract

This article highlights the clinical significance of modern non-invasive diagnostic methods in the diagnosis and monitoring of Drug-Induced Liver Injury (DILI). It analyzes the role of transient elastography and serum biomarkers (specifically, humoral factors) in the early detection of hepatotoxicity developing against the background of polypharmacy, and in the assessment of necroinflammatory and fibrotic processes. The main focus is on diagnostic algorithms that provide a s1.afe and dynamic monitoring alternative to liver biopsy.

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Published

2026-04-06

Issue

Vol. 4 No. 4 (2026): WOM

Section

Articles

License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

How to Cite

CLINICAL SIGNIFICANCE OF NON-INVASIVE DIAGNOSTIC METHODS IN THE MONITORING OF DRUG-INDUCED LIVER INJURY. (2026). Web of Medicine: Journal of Medicine, Practice and Nursing , 4(4), 7-8. https://mail.webofjournals.com/index.php/5/article/view/6197